Endoglin anticorps (AA 258-297)
Aperçu rapide pour Endoglin anticorps (AA 258-297) (ABIN5647366)
Antigène
Voir toutes Endoglin (ENG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 258-297
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Purification
- Antigen affinity purified
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Immunogène
- Amino acids 258-297 (YVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQ) from the human protein were used as the immunogen for the Endoglin antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Endoglin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the Endoglin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Endoglin (ENG)
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Autre désignation
- CD105 / Endoglin
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Sujet
- Endoglin (Osler-Rendu-Weber syndrome 1), also called CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia.
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UniProt
- P17813
Antigène
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