APRT anticorps (AA 5-49)
Aperçu rapide pour APRT anticorps (AA 5-49) (ABIN5647397)
Antigène
Voir toutes APRT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 5-49
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Purification
- Antigen affinity purified
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Immunogène
- Amino acids 5-49 (ELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARH-human) were used as the immunogen for the APRT antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the APRT antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the APRT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- APRT (Adenine Phosphoribosyltransferase (APRT))
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Autre désignation
- APRT
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Sujet
- Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P07741
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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