APRT anticorps (AA 5-49)

N° du produit ABIN5647397

Détail du produit anti-APRT anticorps

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Épitope: AA 5-49

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APRT est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogène: Amino acids 5-49 (ELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARH-human) were used as the immunogen for the APRT antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the APRT antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the APRT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur APRT

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Autre désignation: APRT (APRT Produits)

Synonymes: anticorps Tb07.43M14.200, anticorps Tb07.43M14.180, anticorps C85684, anticorps AMP, anticorps APRTD, anticorps adenine phosphoribosyltransferase, anticorps adenine phosphoribosyl transferase, anticorps CND05020, anticorps Tb927.7.1790, anticorps Tb927.7.1780, anticorps Arnit_0941, anticorps Saut_1231, anticorps Fbal_1180, anticorps PH_RS07970, anticorps PF_RS08760, anticorps PAB_RS02560, anticorps Aprt, anticorps APRT

Sujet: Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P07741

Pathways: Ribonucleoside Biosynthetic Process