MMP13 anticorps (AA 109-154)

N° du produit ABIN5647596

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP13 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour MMP13 anticorps (AA 109-154) (ABIN5647596)

Antigène: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP13 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MMP13 anticorps

Épitope: AA 109-154

Purification: Antigen affinity purified

Immunogène: Amino acids 109-154 (RTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFT-human) were used as the immunogen for the MMP13 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MMP13 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the MMP13 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur MMP13

Antigène: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Autre désignation: MMP13 / Collagenase 3

Sujet: Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene. This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.

UniProt: P45452