CCL17 anticorps (AA 553-582)

N° du produit ABIN7479732

Cet anticorps anti-CCL17 Polyclonal Lapin (ABIN7479732) détecte spécifiquement CCL17 dans WB, ELISA, IHC et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CCL17 anticorps (AA 553-582) (ABIN7479732)

Antigène: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-CCL17 anticorps

Épitope: AA 553-582

Fonction: ABCD2 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 553-582 from the human protein was used as the immunogen for this ABCD2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ABCD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ABCD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CCL17

Antigène: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Autre désignation: ABCD2

Sujet: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.

UniProt: Q9UBJ2