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TECTA anticorps (AA 93-134)

Cet anticorps anti-TECTA est un anticorps Lapin Polyclonal détectant TECTA dans WB et IHC (p). Adapté pour Humain, Souris et Rat.
N° du produit ABIN5647724

Aperçu rapide pour TECTA anticorps (AA 93-134) (ABIN5647724)

Antigène

Voir toutes TECTA Anticorps
TECTA (Tectorin alpha (TECTA))

Reactivité

Humain, Souris, Rat

Hôte

  • 3
  • 2
Lapin

Clonalité

  • 3
  • 2
Polyclonal

Conjugué

  • 5
Cet anticorp TECTA est non-conjugé

Application

  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 2
    • 1
    • 1
    • 1
    AA 93-134

    Purification

    Antigen affinity purified

    Immunogène

    Amino acids 93-134 (RAFVAPFWADVHNGIRGEIYYRETMEPAILKRATKDIRKYFK) from human Alpha Tectorin were used as the immunogen for the TECTA antibody.

    Isotype

    IgG
  • Indications d'application

    Optimal dilution of the TECTA antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

    Restrictions

    For Research Use only
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Stock

    -20 °C

    Stockage commentaire

    After reconstitution, the TECTA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène

    TECTA (Tectorin alpha (TECTA))

    Autre désignation

    TECTA (Alpha Tectorin)

    Sujet

    Alpha Tectorin is a protein that in humans is encoded by the TECTA gene. The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness.

    UniProt

    O75443

    Pathways

    Sensory Perception of Sound
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