Acrosin anticorps (AA 99-127)
Aperçu rapide pour Acrosin anticorps (AA 99-127) (ABIN7479780)
Antigène
Voir toutes Acrosin (ACR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 99-127
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Fonction
- ACR Antibody / Acrosin
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Purification
- Purified
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Immunogène
- A portion of amino acids 99-127 from the human protein was used as the immunogen for this ACR antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the ACR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the ACR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Acrosin (ACR)
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Autre désignation
- ACR
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Sujet
- Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
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UniProt
- P10323
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Pathways
- cAMP Metabolic Process
Antigène
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