QPCT anticorps (AA 262-359)

N° du produit ABIN565166

Il existe 4+ publications pour ce produit. L’anticorps anti-QPCT Polyclonal Souris est utilisé pour la détection de QPCT dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour QPCT anticorps (AA 262-359) (ABIN565166)

Antigène: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp QPCT est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-QPCT anticorps

Épitope: AA 262-359

Fonction: Mouse polyclonal antibody raised against a partial recombinant QPCT.

Séquence: PNSARWFERL QAIEHELHEL GLLKDHSLEG RYFQNYSYGG VIQDDHIPFL RRGVPVLHLI PSPFPEVWHT MDDNEENLDE STIDNLNKIL QVFVLEYL

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: QPCT (NP_036545, 262 a.a. ~ 359 a.a) partial recombinant protein with GST tag.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 50 % glycerol

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-QPCT (ABIN565166)

Morawski, Schilling, Kreuzberger, Waniek, Jäger, Koch, Cynis, Kehlen, Arendt, Hartlage-Rübsamen, Demuth, Roßner: "Glutaminyl cyclase in human cortex: correlation with (pGlu)-amyloid-? load and cognitive decline in Alzheimer's disease." dans: Journal of Alzheimer's disease : JAD, Vol. 39, Issue 2, pp. 385-400, (2014) (PubMed).

Chen, Huang, Kuo, Lo, Lee, Wang: "Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins." dans: The Biochemical journal, Vol. 442, Issue 2, pp. 403-12, (2012) (PubMed).

Hartlage-Rübsamen, Morawski, Waniek, Jäger, Zeitschel, Koch, Cynis, Schilling, Schliebs, Demuth, Rossner: "Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-A? deposits in hippocampus via distinct cellular mechanisms." dans: Acta neuropathologica, Vol. 121, Issue 6, pp. 705-19, (2011) (PubMed).

Morawski, Hartlage-Rübsamen, Jäger, Waniek, Schilling, Schwab, McGeer, Arendt, Demuth, Rossner: "Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease." dans: Acta neuropathologica, Vol. 120, Issue 2, pp. 195-207, (2010) (PubMed).

Détails sur QPCT

Antigène: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Autre désignation: QPCT

Sujet: Full Gene Name: glutaminyl-peptide cyclotransferase
Synonyms: GCT,QC

ID gène: 25797

NCBI Accession: NM_012413