TRIB2 anticorps (AA 254-343)
Aperçu rapide pour TRIB2 anticorps (AA 254-343) (ABIN565396)
Antigène
Voir toutes TRIB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 254-343
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Fonction
- Mouse monoclonal antibody raised against a partial recombinant TRIB2.
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Séquence
- FHDIEPSSLF SKIRRGQFNI PETLSPKAKC LIRSILRREP SERLTSQEIL DHPWFSTDFS VSNSAYGAKE VSDQLVPDVN MEENLDPFFN
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Réactivité croisée
- Humain
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Attributs du produit
- Antibody Reactive Against Recombinant Protein.
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Immunogène
- TRIB2 (NP_067675, 254 a.a. ~ 343 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- In 1x PBS, pH 7.4
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Conseil sur la manipulation
- Aliquot to avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "TRIB2 inhibits Wnt/?-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ?-TrCP, COP1 and Smurf1, in liver cancer cells." dans: FEBS letters, Vol. 588, Issue 23, pp. 4334-41, (2014) (PubMed).
: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." dans: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).
: "Ubiquitin E3 ligase SCF(?-TRCP) regulates TRIB2 stability in liver cancer cells." dans: Biochemical and biophysical research communications, Vol. 441, Issue 3, pp. 555-9, (2013) (PubMed).
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- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
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Autre désignation
- TRIB2
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Sujet
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Full Gene Name: tribbles homolog 2 (Drosophila)
Synonyms: C5FW,GS3955,TRB2 -
ID gène
- 28951
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NCBI Accession
- NM_021643
Antigène
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