RAD18 anticorps (AA 332-430)

N° du produit ABIN566046

Cité dans 7 publications. Cet anticorps anti-RAD18 Monoclonal Souris (Clone 3H7) (ABIN566046) détecte spécifiquement RAD18 dans WB, ELISA, IF, IHC (p) et RNAi. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RAD18 anticorps (AA 332-430) (ABIN566046)

Antigène: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAD18 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Clone: 3H7

Détail du produit anti-RAD18 anticorps

Épitope: AA 332-430

Fonction: Mouse monoclonal antibody raised against a partial recombinant RAD18.

Séquence: EKEIDEIHSK YRKKHKSEFQ LLVDQARKGY KKIAGMSQKT VTITKEDEST EKLSSVCMGQ EDNMTSVTNH FSQSKLDSPE ELEPDREEDS SSCIDIQEV

Réactivité croisée: Humain, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: RAD18 (NP_064550, 332 a.a. ~ 430 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RAD18 (ABIN566046)

Sy, Jiang, O, Deng, Huen: "The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks." dans: Nucleic acids research, Vol. 41, Issue 18, pp. 8572-80, (2013) (PubMed).

Wong, Aguissa-Touré, Wani, Khosravi, Martinka, Martinka, Li: "Elevated expression of Rad18 regulates melanoma cell proliferation." dans: Pigment cell & melanoma research, Vol. 25, Issue 2, pp. 213-8, (2012) (PubMed).

Kato, Waki, Umezawa, Aoki, Utsugi, Ohtsu, Murakami: "Phosphorylation of human INO80 is involved in DNA damage tolerance." dans: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 433-8, (2012) (PubMed).

Wong, Lin, Khosravi, Piche, Jafarnejad, Chen, Li: "Tumour suppressor ING1b maintains genomic stability upon replication stress." dans: Nucleic acids research, Vol. 39, Issue 9, pp. 3632-42, (2011) (PubMed).

Yanagihara, Kobayashi, Tateishi, Kato, Matsuura, Tauchi, Yamada, Takezawa, Sugasawa, Masutani, Hanaoka, Weemaes, Mori, Zou, Komatsu: "NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol ?-dependent translesion DNA synthesis." dans: Molecular cell, Vol. 43, Issue 5, pp. 788-97, (2011) (PubMed).

Hicks, Chute, Paulsen, Ragland, Howlett, Guéranger, Glover, Canman: "Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links." dans: Molecular and cellular biology, Vol. 30, Issue 5, pp. 1217-30, (2010) (PubMed).

Kobayashi, Okui, Asaithamby, Burma, Chen, Tanimoto, Matsuura, Komatsu, Chen: "WRN participates in translesion synthesis pathway through interaction with NBS1." dans: Mechanisms of ageing and development, Vol. 131, Issue 6, pp. 436-44, (2010) (PubMed).

Détails sur RAD18

Antigène: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Autre désignation: RAD18

Sujet: Full Gene Name: RAD18 homolog (S. cerevisiae)
Synonyms: RNF73

ID gène: 56852

NCBI Accession: NM_020165