SMURF1 anticorps (AA 165-268)

N° du produit ABIN566098

Détail du produit anti-SMURF1 anticorps

Antigène: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Épitope: AA 165-268

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMURF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)

Fonction: Mouse monoclonal antibody raised against a partial recombinant SMURF1.

Séquence: DSGPGRPLSC FMEEPAPYTD STGAAAGGGN CRFVESPSQD QRLQAQRLRN PDVRGSLQTP QNRPHGHQSP ELPEGYEQRT TVQGQVYFLH TQTGVSTWHD PRIP

Réactivité croisée: Humain, Souris

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: SMURF1 (NP_065162, 165 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1D7

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-SMURF1 (ABIN566098)

Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." dans: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).

Murakami, Mathew, Huang, Farahani, Peng, Olson, Etlinger: "Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 7, pp. 805-13, (2010) (PubMed).

Détails sur SMURF1

Antigène: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Autre désignation: SMURF1 (SMURF1 Produits)

Synonymes: anticorps 4930431E10Rik, anticorps mKIAA1625, anticorps RGD1309707, anticorps SMAD specific E3 ubiquitin protein ligase 1, anticorps E3 ubiquitin-protein ligase SMURF1, anticorps SMAD specific E3 ubiquitin protein ligase 1 L homeolog, anticorps SMURF1, anticorps LOC100540915, anticorps smurf1, anticorps Smurf1, anticorps smurf1.L

Sujet: Full Gene Name: SMAD specific E3 ubiquitin protein ligase 1
Synonyms: KIAA1625

ID gène: 57154

NCBI Accession: NM_020429

Pathways: Regulation of Cell Size