RXFP1 anticorps (AA 68-162)

N° du produit ABIN566200

Cet anticorps Souris Monoclonal détecte spécifiquement RXFP1 dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 8+ publications.

Aperçu rapide pour RXFP1 anticorps (AA 68-162) (ABIN566200)

Antigène: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RXFP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 3E3

Détail du produit anti-RXFP1 anticorps

Épitope: AA 68-162

Fonction: Mouse monoclonal antibody raised against a partial recombinant LGR7.

Séquence: WSMQFDKYFA SYYKMTSQYP FEAETPECLV GSVPVQCLCQ GLELDCDETN LRAVPSVSSN VTAMSLQWNL IRKLPPDCFK NYHDLQKLYL QNNKI

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: LGR7 (NP_067647, 68 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RXFP1 (ABIN566200)

Jelinic, Leo, Post Uiterweer, Sandow, Gooi, Wlodek, Conrad, Parkington, Tare, Parry: "Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 1, pp. 275-87, (2014) (PubMed).

Ferlin, Menegazzo, Gianesello, Selice, Foresta: "Effect of relaxin on human sperm functions." dans: Journal of andrology, Vol. 33, Issue 3, pp. 474-82, (2012) (PubMed).

Soh, Tiwari, Mahendroo, Conrad, Parry: "Relaxin regulates hyaluronan synthesis and aquaporins in the cervix of late pregnant mice." dans: Endocrinology, Vol. 153, Issue 12, pp. 6054-64, (2012) (PubMed).

Vandevoort, Mtango, Latham, Stewart: "Primate preimplantation embryo is a target for relaxin during early pregnancy." dans: Fertility and sterility, Vol. 96, Issue 1, pp. 203-7, (2011) (PubMed).

Ferlin, Pepe, Facciolli, Gianesello, Foresta: "Relaxin stimulates osteoclast differentiation and activation." dans: Bone, Vol. 46, Issue 2, pp. 504-13, (2010) (PubMed).

Vodstrcil, Shynlova, Verlander, Wlodek, Parry: "Decreased expression of the rat myometrial relaxin receptor (RXFP1) in late pregnancy is partially mediated by the presence of the conceptus." dans: Biology of reproduction, Vol. 83, Issue 5, pp. 818-24, (2010) (PubMed).

Feng, Agoulnik, Truong, Li, Creighton, Kaftanovskaya, Pereira, Han, Lopez-Berestein, Klonisch, Ittmann, Sood, Agoulnik: "Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis." dans: Endocrine-related cancer, Vol. 17, Issue 4, pp. 1021-33, (2010) (PubMed).

Kern, Bryant-Greenwood: "Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells." dans: Endocrinology, Vol. 150, Issue 5, pp. 2419-28, (2009) (PubMed).

Détails sur RXFP1

Antigène: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Autre désignation: RXFP1

Sujet: Full Gene Name: relaxin/insulin-like family peptide receptor 1
Synonyms: LGR7,LGR7.1,LGR7.10,LGR7.2,MGC138347,MGC142177,RXFPR1

ID gène: 59350

NCBI Accession: NM_021634

Pathways: Myometrial Relaxation and Contraction