DNAI2 anticorps (AA 1-593)

N° du produit ABIN566265

Cet anticorps anti-DNAI2 est un anticorps Souris Monoclonal détectant DNAI2 dans WB, ELISA et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 6+ publications.

Aperçu rapide pour DNAI2 anticorps (AA 1-593) (ABIN566265)

Antigène: DNAI2 (Dynein, Axonemal, Intermediate Chain 2 (DNAI2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DNAI2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 1C8

Détail du produit anti-DNAI2 anticorps

Épitope: AA 1-593

Fonction: Mouse monoclonal antibody raised against a full length recombinant DNAI2.

Séquence: MEIVYVYVKK RSEFGKQCNF SDRQAELNID IMPNPELAEQ FVERNPVDTG IQCSISMSEH EANSERFEME TRGVNHVEGG WPKDVNPLEL EQTIRFRKKV EKDENYVNAI MQLGSIMEHC IKQNNAIDIY EEYFNDEEAM EVMEEDPSAK TINVFRDPQE IKRAATHLSW HPDGNRKLAV AYSCLDFQRA PVGMSSDSYI WDLENPNKPE LALKPSSPLV TLEFNPKDSH VLLGGCYNGQ IACWDTRKGS LVAELSTIES SHRDPVYGTI WLQSKTGTEC FSASTDGQVM WWDIRKMSEP TEVVILDITK KEQLENALGA ISLEFESTLP TKFMVGTEQG IVISCNRKAK TSAEKIVCTF PGHHGPIYAL QRNPFYPKNF LTVGDWTARI WSEDSRESSI MWTKYHMAYL TDAAWSPVRP TVFFTTRMDG TLDIWDFMFE QCDPTLSLKD NGCLIACGSQ LGTTTLLEVS PGLSTLQRNE KNVASSMFER ETRREKILEA RHREMRLKEK GKAEGRDEEQ TDEELAVDLE ALVSKAEEEF FDIIFTELKK KEADAIKLTP VPQQPSPEED QVVEEGEEAA GEEGDEEVEE DLA

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: DNAI2 (AAH39582, 1 a.a. ~ 593 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-DNAI2 (ABIN566265)

Ben Khelifa, Coutton, Zouari, Karaouzène, Rendu, Bidart, Yassine, Pierre, Delaroche, Hennebicq, Grunwald, Escalier, Pernet-Gallay, Jouk, Thierry-Mieg, Touré, Arnoult, Ray: "Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella." dans: American journal of human genetics, Vol. 94, Issue 1, pp. 95-104, (2014) (PubMed).

Dong, Shinohara, Botilde, Nabeshima, Asai, Fukumoto, Hasegawa, Matsuo, Takeda, Shiratori, Nakamura, Hamada: "Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm." dans: The Journal of cell biology, Vol. 204, Issue 2, pp. 203-13, (2014) (PubMed).

Diggle, Moore, Mali, zur Lage, Ait-Lounis, Schmidts, Shoemark, Garcia Munoz, Halachev, Gautier, Yeyati, Bonthron, Carr, Hayward, Markham, Hope, von Kriegsheim, Mitchison, Jackson, Durand, Reith et al.: "HEATR2 plays a conserved role in assembly of the ciliary motile apparatus. ..." dans: PLoS genetics, Vol. 10, Issue 9, pp. e1004577, (2014) (PubMed).

Tarkar, Loges, Slagle, Francis, Dougherty, Tamayo, Shook, Cantino, Schwartz, Jahnke, Olbrich, Werner, Raidt, Pennekamp, Abouhamed, Hjeij, Köhler, Griese, Li, Lemke, Klena, Liu, Gabriel, Tobita et al.: "DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." dans: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).

Loges, Olbrich, Fenske, Mussaffi, Horvath, Fliegauf, Kuhl, Baktai, Peterffy, Chodhari, Chung, Rutman, OCallaghan, Blau, Tiszlavicz, Voelkel, Witt, Zietkiewicz, Neesen, Reinhardt, Mitchison, Omran: "DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm." dans: American journal of human genetics, Vol. 83, Issue 5, pp. 547-58, (2008) (PubMed).

Omran, Kobayashi, Olbrich, Tsukahara, Loges, Hagiwara, Zhang, Leblond, OToole, Hara, Mizuno, Kawano, Fliegauf, Yagi, Koshida, Miyawaki, Zentgraf, Seithe, Reinhardt, Watanabe, Kamiya, Mitchell, Takeda: "Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins." dans: Nature, Vol. 456, Issue 7222, pp. 611-6, (2008) (PubMed).

Détails sur DNAI2

Antigène: DNAI2 (Dynein, Axonemal, Intermediate Chain 2 (DNAI2))

Autre désignation: DNAI2

Sujet: Full Gene Name: dynein, axonemal, intermediate chain 2
Synonyms: CILD9

ID gène: 64446