Aryl Hydrocarbon Receptor anticorps (AA 619-848)

N° du produit ABIN5663909

Cet anticorps Lapin Polyclonal détecte spécifiquement Aryl Hydrocarbon Receptor dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour Aryl Hydrocarbon Receptor anticorps (AA 619-848) (ABIN5663909)

Antigène: Aryl Hydrocarbon Receptor (AHR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aryl Hydrocarbon Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Aryl Hydrocarbon Receptor anticorps

Épitope: AA 619-848

Séquence: LEQQQQHHQK QVVVEPQQQL CQKMKHMQVN GMFENWNSNQ FVPFNCPQQD PQQYNVFTDL HGISQEFPYK SEMDSMPYTQ NFISCNQPVL PQHSKCTELD YPMGSFEPSP YPTTSSLEDF VTCLQLPENQ KHGLNPQSAI ITPQTCYAGA VSMYQCQPEP QHTHVGQMQY NPVLPGQQAF LNKFQNGVLN ETYPAELNNI NNTQTTTHLQ PLHHPSEARP FPDLTSSGFL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 619-848 of human AHR (NP_001612.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Aryl Hydrocarbon Receptor (ABIN5663909)

Liu, Zhou, Zhang, Ding, Du, Hu: "1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells." dans: International journal of cancer, Vol. 143, Issue 6, pp. 1516-1529, (2018) (PubMed).

Détails sur Aryl Hydrocarbon Receptor

Antigène: Aryl Hydrocarbon Receptor (AHR)

Autre désignation: AHR

Sujet: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm, upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.,AHR,bHLHe76,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,AHR

Poids moléculaire: 96 kDa

ID gène: 196

UniProt: P35869

Pathways: Regulation of Cell Size