Recombinant Polysialic Acid anticorps

N° du produit ABIN5668053

Détail du produit

Antigène: Polysialic Acid

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Specificité: Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of α2,8-linked sialic acid of Escherichia coli K1.

Attributs du produit:

OriginalSpeciesName: Mouse

OriginalFormat: IgG2a

Purification: Purified antibody.

Immunogène: Homopolymers of alpha2,8-linked sialic acid of Escherichia coli K1.

Clone: 735

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody recognises an unusual postranslational modification on neural cell adhesion molecules important in synaptogenesis, oncogenesis (particularly small-cell lung cancer) and development of organs such as the kidney (studied in rats, Lackie et al. 1990). In addition to various studies on human cells, the antibody, has also been used the study the fine-composition of poly-sialic acid composition in mice (Galuska et al. 2006).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détail du antigène

Antigène: Polysialic Acid

Sujet: PSA, N-CAM, neural cell adhesion molecule, polySA