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Recombinant TNF alpha (Infliximab Biosimilar) anticorps

Cet anticorps anti-TNF alpha (Infliximab Biosimilar) est un anticorps Human Chimeric détectant TNF alpha (Infliximab Biosimilar) dans FACS, in vivo et ELISA. Adapté pour Humain.
N° du produit ABIN5668147

Aperçu rapide pour Recombinant TNF alpha (Infliximab Biosimilar) anticorps (ABIN5668147)

Antigène

TNF alpha (Infliximab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 2
  • 1
  • 1
  • 1
Human

Clonalité

  • 3
  • 2
Chimeric

Conjugué

  • 5
Cet anticorp TNF alpha (Infliximab Biosimilar) est non-conjugé

Application

  • 3
  • 3
  • 3
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo), ELISA

Clone

CA2
  • Fonction

    Anti-TNF alpha [cA2 (Infliximab)], Human IgG1, kappa

    Specificité

    Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.

    Attributs du produit

    Original Species of Ab: Human

    Original Format of Ab: IgG1

    Purification

    Protein A affinity purified

    Pureté

    > 98 % as determined by SDS-PAGE

    niveau d'endotoxine

    Endotoxin is < 1.0 EU/mg as determined by the LAL method

    Immunogène

    Purified recombinant human TNF (rTNF).

    Isotype

    IgG1 kappa
  • Indications d'application

    This antibody can be used to detect and neutralize human TNF alpha. Unlike Adalimumab (Ab00718), Infliximab does not bind to mouse TNF alpha (Arnoult 2017, PMID: 28584008).

    Commentaires

    NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This is a chimeric antibody created for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    TNF alpha (Infliximab Biosimilar)

    Classe de substances

    Biosimilar

    Sujet

    TNF-α, TNFα, TNFSF, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, TNFa

    UniProt

    P01375
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