Recombinant VEGF anticorps
Aperçu rapide pour Recombinant VEGF anticorps (ABIN5668149)
Antigène
Voir toutes VEGF AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-VEGF [A.4.6.1], Mouse IgG1, kappa
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Specificité
- Binds native and reduced human VEGF (isoform 165), with a Kd of 0.8 nm determined for the original clone.
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Réactivité croisée
- Rat
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Attributs du produit
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogène
- Recombinant human VEGF.
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Isotype
- IgG1 kappa
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Indications d'application
- This is the parental antibody clone to the humanized, therapeutic antibody Bevacizumab (marketed as Avastin) binding to VEGF. VEGF is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- VEGF (Vascular Endothelial Growth Factor (VEGF))
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Autre désignation
- VEGF
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Sujet
- VEGF-A, Vascular Endothelial Growth Factor, VEGFA, Vascular Permeability Factor, VPF
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UniProt
- P15692
Antigène
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