Recombinant ITGA4 (Natalizumab Biosimilar) anticorps
Reactivité: Humain
FACS, BR
Hôte: Human
Monoclonal
unconjugated
Recombinant Antibody
(1 reference)-
- Antigène Tous les produits ITGA4 (Natalizumab Biosimilar)
- ITGA4 (Natalizumab Biosimilar)
- Type d'anticorp
- Recombinant Antibody
- Reactivité
- Humain
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Hôte
-
Human
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ITGA4 (Natalizumab Biosimilar) est non-conjugé
- Application
- Flow Cytometry (FACS), Blocking Reagent (BR)
- Specificité
- This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
- Attributs du produit
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OriginalSpeciesName: Human
OriginalFormat: IgG4
- Purification
- Purified antibody.
- Pureté
- > 98 % as determined by SDS-PAGE
- niveau d'endotoxine
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogène
- The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
- Isotype
- IgG4 kappa
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anti-ITGA4 (Natalizumab Biosimilar) antibody
Reactivité: Humain FACS, BR Hôte: Lapin Chimeric unconjugated Recombinant Antibody
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- Indications d'application
- This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
- Commentaires
-
NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % Proclin 300.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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-
: "An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family." dans: PloS one, Vol. 17, Issue 9, pp. e0274667, (2022) (PubMed).
-
: "An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family." dans: PloS one, Vol. 17, Issue 9, pp. e0274667, (2022) (PubMed).
-
- Antigène
- ITGA4 (Natalizumab Biosimilar)
- Abstract
- ITGA4 (Natalizumab Biosimilar) Produits
- Synonymes
- anticorps CD49D, anticorps IA4, anticorps integrin subunit alpha 4, anticorps ITGA4
- Sujet
- CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV
- UniProt
- P13612
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