Recombinant CD33 (Gemtuzumab Biosimilar) anticorps
Aperçu rapide pour Recombinant CD33 (Gemtuzumab Biosimilar) anticorps (ABIN5668210)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Anti-CD33 [hP67.6 (Gemtuzumab)], Human IgG4, kappa
-
Specificité
- Recognises human CD33.
-
Attributs du produit
-
Original Species of Ab: Human
Original Format of Ab: IgG4
-
Purification
- Protein A affinity purified
-
Pureté
- > 98 % as determined by SDS-PAGE
-
niveau d'endotoxine
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
-
Immunogène
- Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
-
Isotype
- IgG4 kappa
-
-
anti-CD33 (Gemtuzumab Biosimilar) antibody
Research Grade Reactivité: Humain FACS Hôte: Humanized Monoclonal unconjugated Recombinant Antibody
anti-CD33 (Gemtuzumab Biosimilar) antibodyReactivité: Humain FACS, IF Hôte: Lapin Chimeric HP67-6 unconjugated Recombinant Antibody
-
-
Indications d'application
- A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % Proclin 300.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- CD33 (Gemtuzumab Biosimilar)
-
Classe de substances
- Biosimilar
-
Sujet
- Siglec-3
-
UniProt
- P20138
Antigène
-
