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Recombinant CD33 (Gemtuzumab Biosimilar) anticorps

Reactivité: Humain FACS, IF Hôte: Human Monoclonal HP67-6 unconjugated Recombinant Antibody
N° du produit ABIN5668210
  • Antigène Tous les produits CD33 (Gemtuzumab Biosimilar)
    CD33 (Gemtuzumab Biosimilar)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    Humain
    Hôte
    • 2
    • 2
    • 1
    • 1
    Human
    Clonalité
    • 6
    Monoclonal
    Conjugué
    • 6
    Cet anticorp CD33 (Gemtuzumab Biosimilar) est non-conjugé
    Application
    • 5
    • 4
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Specificité
    Recognises human CD33.
    Attributs du produit

    OriginalSpeciesName: Human

    OriginalFormat: IgG4

    Purification
    Purified antibody.
    Pureté
    > 98 % as determined by SDS-PAGE
    niveau d'endotoxine
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogène
    Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
    Clone
    HP67-6
    Isotype
    IgG4 kappa
  • Indications d'application
    A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène
    CD33 (Gemtuzumab Biosimilar)
    Abstract
    CD33 (Gemtuzumab Biosimilar) Produits
    Synonymes
    anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps CD33 molecule, anticorps CD33
    Classe de substances
    Biosimilar
    Sujet
    Siglec-3
    UniProt
    P20138
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