Recombinant ErbB2/Her2 (Trastuzumab Biosimilar) anticorps

N° du produit ABIN5668227

L’anticorps Lapin Chimeric anti-ErbB2/Her2 (Trastuzumab Biosimilar) a été validé pour FACS, ELISA et IHC. Il convient pour détecter ErbB2/Her2 (Trastuzumab Biosimilar) dans des échantillons de Humain.

Aperçu rapide pour Recombinant ErbB2/Her2 (Trastuzumab Biosimilar) anticorps (ABIN5668227)

Antigène: ErbB2/Her2 (Trastuzumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp ErbB2/Her2 (Trastuzumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)

Clone: 4D5-8

Détail du produit anti-ErbB2/Her2 (Trastuzumab Biosimilar) anticorps

Fonction: Anti-erbB-2 (Her-2/neu) [4D5-8 (trastuzumab)], Rabbit IgG, kappa

Specificité: Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30 % of invasive breast cancers and 70 % of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.

Attributs du produit:

Original Species of Ab: Human

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Pureté: > 98 % as determined by SDS-PAGE

niveau d'endotoxine: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogène: A431 cells (human epidermoid carcinoma) (over)expressing EGFR.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody binds to erbB-2/Her-2/neu has therapeutic indications particularly in the treatment of breast cancer (c.f. Herceptin). It can also be used to detect HER-2 by flow cytometry or IHC (Glazyrin 2007).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur ErbB2/Her2 (Trastuzumab Biosimilar)

Antigène: ErbB2/Her2 (Trastuzumab Biosimilar)

Classe de substances: Biosimilar

Sujet: CD340, Metastatic lymph node gene 19 protein (MLN 19), Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, p185HER2, EGFR

UniProt: P04626