PHOX2B anticorps (C-Term)

N° du produit ABIN5671377

Cet anticorps Lapin Polyclonal détecte spécifiquement PHOX2B dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PHOX2B anticorps (C-Term) (ABIN5671377)

Antigène: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHOX2B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PHOX2B anticorps

Épitope: C-Term

Fonction: PHOX2B Antibody - C-terminal region

Séquence: RAAAAAAAAA KNGSSGKKSD SSRDDESKEA KSTDPDSTGG PGPNPNPTPS

Attributs du produit: This is a rabbit polyclonal antibody against PHX2B. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHX2B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74127-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PHOX2B

Antigène: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Autre désignation: PHOX2B

Sujet:

Background Information: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.

Gene Name: paired like homeobox 2B

Alternative Symbols: CCHS, PMX2B, NBLST2, NBPhox

Protein Name: paired mesoderm homeobox protein 2B

Poids moléculaire: 34kDa

ID gène: 8929

NCBI Accession: NP_003915

UniProt: Q99453