XRN2 anticorps (C-Term)

N° du produit ABIN5671406

Cet anticorps anti-XRN2 est un anticorps Lapin Polyclonal détectant XRN2 dans WB. Adapté pour Souris.

Aperçu rapide pour XRN2 anticorps (C-Term) (ABIN5671406)

Antigène: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XRN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-XRN2 anticorps

Épitope: C-Term

Séquence: QNAAFQPNQY QMLGGPGGYP PRRDDHRGGR QGYPREGRKY PLPPPSGRYS

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of Mouse XRN2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur XRN2

Antigène: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Autre désignation: XRN2

Sujet: Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites.

Protein Size: 951

ID gène: 24128

NCBI Accession: NM_011917, NP_036047

UniProt: Q9DBR1