PRUNE2 anticorps (C-Term)

N° du produit ABIN5671800

L’anticorps Lapin Polyclonal anti-PRUNE2 a été validé pour WB. Il convient pour détecter PRUNE2 dans des échantillons de Humain.

Aperçu rapide pour PRUNE2 anticorps (C-Term) (ABIN5671800)

Antigène: PRUNE2 (Prune Homolog 2 (PRUNE2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRUNE2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRUNE2 anticorps

Épitope: C-Term

Séquence: LNDTHPRRIK LTAPNINLSL DQSEGSILSD DNLDSPDEID INVDELDTPD

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PRUNE2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRUNE2

Antigène: PRUNE2 (Prune Homolog 2 (PRUNE2))

Autre désignation: PRUNE2

Sujet: The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants.

Alias Symbols: BMCC1, BNIPXL, C9orf65, KIAA0367

Protein Size: 352

ID gène: 158471

NCBI Accession: NM_001308047, NP_001294976