PLSCR3 anticorps (N-Term)

N° du produit ABIN5673452

Cet anticorps anti-PLSCR3 Polyclonal Lapin (ABIN5673452) détecte spécifiquement PLSCR3 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PLSCR3 anticorps (N-Term) (ABIN5673452)

Antigène: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLSCR3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PLSCR3 anticorps

Épitope: N-Term

Séquence: PPKGYAPSPP PPYPVTPGYP EPALHPGPGQ APVPAQVPAP APGFALFPSP

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PLSCR3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PLSCR3

Antigène: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Autre désignation: PLSCR3

Sujet: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.

Protein Size: 295

ID gène: 57048

NCBI Accession: NM_001201576, NP_001188505

UniProt: Q9NRY6

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis