TMEM43 anticorps (N-Term)

N° du produit ABIN5673734

Cet anticorps anti-TMEM43 Polyclonal Lapin (ABIN5673734) détecte spécifiquement TMEM43 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TMEM43 anticorps (N-Term) (ABIN5673734)

Antigène: TMEM43 (Transmembrane Protein 43 (TMEM43))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM43 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TMEM43 anticorps

Épitope: N-Term

Séquence: ANYSSTSTRR EHVKVKTSSQ PGFLERLSET SGGMFVGLMA FLLSFYLIFT

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TMEM43

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TMEM43

Antigène: TMEM43 (Transmembrane Protein 43 (TMEM43))

Autre désignation: TMEM43

Sujet: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Alias Symbols: LUMA, ARVC5, ARVD5, EDMD7

Protein Size: 400

ID gène: 79188

NCBI Accession: NM_024334, NP_077310

UniProt: Q9BTV4