TDRKH anticorps (C-Term)
Aperçu rapide pour TDRKH anticorps (C-Term) (ABIN5673744)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- DMATETDASL STLLTETKKS SGEITHTLSC LSLSEAASMS GDDNLEDDYL
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human TDRKH
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TDRKH (Tudor and KH Domain Containing (TDRKH))
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Autre désignation
- TDRKH
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Sujet
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Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.
Alias Symbols: TDRD2
Protein Size: 561 -
ID gène
- 11022
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NCBI Accession
- NM_001083963, NP_001077432
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UniProt
- Q9Y2W6
Antigène
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