DUSP11 anticorps (C-Term)
Aperçu rapide pour DUSP11 anticorps (C-Term) (ABIN5673780)
Antigène
Voir toutes DUSP11 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- HTQTQSLQQS VRKFSENPHV YQRHHLPPPG PPGEDYSHRR YSWNVKPNAS
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human DUSP11
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))
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Autre désignation
- DUSP11
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Sujet
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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
Alias Symbols: PIR1
Protein Size: 330 -
ID gène
- 8446
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NCBI Accession
- NM_003584, NP_003575
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UniProt
- O75319
Antigène
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