FAM57A anticorps (Middle Region)
Aperçu rapide pour FAM57A anticorps (Middle Region) (ABIN5673967)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- ELSTPFVSLG RVLIQLKQQH TLLYKVNGIL TLATFLSCRI LLFPFMYWSY
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human FAM57A
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))
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Autre désignation
- FAM57A
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Sujet
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The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CT120
Protein Size: 225 -
ID gène
- 79850
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NCBI Accession
- NM_024792, NP_079068
Antigène
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