Thrombomodulin anticorps (AA 21-120)
Aperçu rapide pour Thrombomodulin anticorps (AA 21-120) (ABIN5674993)
Antigène
Voir toutes Thrombomodulin (THBD) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-120
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Réactivité croisée
- Humain, Souris
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Homologie
- Dog,Cow,Sheep
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Thrombomodulin
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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: "Unfractionated heparin protects the protein C system against lipopolysaccharide-induced damage in vivo and in vitro." dans: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5515-5522, (2017) (PubMed).
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: "Unfractionated heparin protects the protein C system against lipopolysaccharide-induced damage in vivo and in vitro." dans: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5515-5522, (2017) (PubMed).
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- Thrombomodulin (THBD)
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Autre désignation
- Thrombomodulin
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Sujet
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Synonyms: Thrombomodulin, CD 141, CD141, CD141 antigen, Fetomodulin, THBD, THRM, TM, AHUS 6, AHUS6, BDCA 3, BDCA3, THPH12, TRBM_HUMAN
Background: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
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ID gène
- 7056
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UniProt
- P07204
Antigène
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