KAT5 anticorps (pSer86)

N° du produit ABIN5675404

Détail du produit anti-KAT5 anticorps

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Épitope: pSer86

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthesised phosphopeptide derived from human KAT5 around the phosphorylation site of Ser86

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur KAT5

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Autre désignation: KAT5 (KAT5 Produits)

Synonymes: anticorps 6121, anticorps CG6121, anticorps DmEG0007.7, anticorps Dmel/TIP60, anticorps Dmel\\CG6121, anticorps Dmel\\TIP60, anticorps EG0007.7, anticorps EG:EG0007.7, anticorps TIP60, anticorps dTIP60, anticorps dTip60, anticorps dmHAG405, anticorps im:6908768, anticorps wu:fb55b08, anticorps zgc:110752, anticorps ESA1, anticorps HTATIP, anticorps HTATIP1, anticorps PLIP, anticorps TIP, anticorps ZC2HC5, anticorps cPLA2, anticorps AI839539, anticorps CPLA2, anticorps Htatip, anticorps Htatip1, anticorps Tip55, anticorps Tip60, anticorps K(lysine) acetyltransferase 5a, anticorps lysine acetyltransferase 5, anticorps Tat interactive protein 60kDa, anticorps histone acetyltransferase Tip60, anticorps tip60, putative, anticorps K(lysine) acetyltransferase 5b, anticorps K(lysine) acetyltransferase 5, anticorps kat5a, anticorps KAT5, anticorps Tip60, anticorps LOC413101, anticorps LOC5579231, anticorps Smp_053140, anticorps kat5b, anticorps Kat5

Sujet:

Synonyms: Histone acetyltransferase KAT5, KAT5, 60 kDa Tat-interactive protein, Tip60, Histone acetyltransferase HTATIP, HIV-1 Tat interactive protein, Lysine acetyltransferase 5, cPLA(2)-interacting protein, KAT5, HTATIP, TIP60

Background: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

ID gène: 10524

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway