MAGI3 anticorps (AA 181-280) (Biotin)

N° du produit ABIN5675611

L’anticorps anti-MAGI3 Polyclonal Lapin est utilisé pour la détection de MAGI3 dans des échantillons de Souris. Il a été validé pour WB, ELISA, IHC (fro) et IHC (p).

Aperçu rapide pour MAGI3 anticorps (AA 181-280) (Biotin) (ABIN5675611)

Antigène: MAGI3 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGI3 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MAGI3 anticorps (Biotin)

Épitope: AA 181-280

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MAGI3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MAGI3

Antigène: MAGI3 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))

Autre désignation: MAGI3

Sujet:

Synonyms: dJ730K3.2, MAGI-3, magi3, MAGI3_HUMAN, Membrane Associated Guanylate kinase Related 3, Membrane-associated guanylate kinase, Membrane-associated guanylate kinase inverted 3, RP4-730K3.1, SLIPR, WW and PDZ domain-containing protein 3

Background: Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.

ID gène: 260425

UniProt: Q5TCQ9