MAD2L1 anticorps

N° du produit ABIN567786

Cet anticorps anti-MAD2L1 est un anticorps Souris Monoclonal détectant MAD2L1 dans WB et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour MAD2L1 anticorps (ABIN567786)

Antigène: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAD2L1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 2G9

Détail du produit anti-MAD2L1 anticorps

Specificité: This antibody reacts with MAD2 (25 kDa) on Western blotting and Immunoprecipitation.

Purification: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogène: Recombinant Human MAD2.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur MAD2L1

Antigène: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Autre désignation: MAD2L1

Sujet: Some of the spindle checkpoint components are evolutionarily conserved from yeast to human. They include mitotic arrest deficiency 1 (MAD1), MAD2, MAD3/BUBR1, budding uninhibited by benomyl 1 (BUB1), BUB3, and monopolar spindle 1 (MPS1). MAD1 interacts with several checkpoint proteins, forming a complex with MAD2 and recruiting MAD2 to unattached kinetochores. MAD1 and Cdc20 can bind MAD2, but these two bindings are exclusive. They share a 10-residue MAD2-binding motif. It has been suggested that MAD1 acts as a positive regulator and a competitive inhibitor of the MAD2-Cdc20 complex.Synonyms: MAD2, Mitotic spindle assembly checkpoint protein MAD2A

ID gène: 4085

NCBI Accession: NP_002349

UniProt: Q13257