MAD2L1 anticorps

N° du produit ABIN567786

Cet anticorps anti-MAD2L1 Monoclonal Souris (Clone 2G9) (ABIN567786) détecte spécifiquement MAD2L1 dans WB et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MAD2L1 anticorps (ABIN567786)

Antigène: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAD2L1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 2G9

Détail du produit anti-MAD2L1 anticorps

Specificité: This antibody reacts with MAD2 (25 kDa) on Western blotting and Immunoprecipitation.

Purification: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogène: Recombinant Human MAD2.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur MAD2L1

Antigène: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Autre désignation: MAD2L1

Sujet: Some of the spindle checkpoint components are evolutionarily conserved from yeast to human. They include mitotic arrest deficiency 1 (MAD1), MAD2, MAD3/BUBR1, budding uninhibited by benomyl 1 (BUB1), BUB3, and monopolar spindle 1 (MPS1). MAD1 interacts with several checkpoint proteins, forming a complex with MAD2 and recruiting MAD2 to unattached kinetochores. MAD1 and Cdc20 can bind MAD2, but these two bindings are exclusive. They share a 10-residue MAD2-binding motif. It has been suggested that MAD1 acts as a positive regulator and a competitive inhibitor of the MAD2-Cdc20 complex.Synonyms: MAD2, Mitotic spindle assembly checkpoint protein MAD2A

ID gène: 4085

NCBI Accession: NP_002349

UniProt: Q13257