POU2F1 anticorps

N° du produit ABIN567788

L’anticorps anti-POU2F1 Monoclonal Souris est utilisé pour la détection de POU2F1 dans des échantillons de Humain et Souris. Il a été validé pour WB, IP et EMSA.

Aperçu rapide pour POU2F1 anticorps (ABIN567788)

Antigène: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp POU2F1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Electrophoretic Mobility-Shift Assay (EMSA)

Clone: YL15

Détail du produit anti-POU2F1 anticorps

Specificité: This antibody reacts with Oct-1 (90 kDa) on Western blotting. YL15 recognizes the POU-domain linker region of Human Oct-1.

Purification: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogène: Recombinant full-length Human Oct-1.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur POU2F1

Antigène: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Autre désignation: POU2F1 / OCT1

Sujet: Octamer transcrIPPtional factor 1 (Oct-1) is a 90 kDa transcrIPPtion factor that binds to the octamer motif ATTTGCAT. This ubiquitous regulatory element is most conspicuous in B cells, where it is found in every immunoglobulin (Ig) promoter and in most Ig enhancers. In addition, Oct-1 binding also activates the promoters of the genes for some small nuclear RNAs (snRNA) and for histone H2B. Oct-1 protein is expressed in multIPPle tissues although some Oct-1 isoforms appear to be tissue specific and the homologous Oct-2 appears to be restricted in expression to B-cells. At least in B-cells, the Oct proteins bind to DNA together with another protein transcrIPPtion factor, octamer binding factor-1 (OBF-1), to form a ternary complex.Synonyms: NF-A1, OTF1, Oct-1, Octamer-binding protein 1, Octamer-binding transcription factor 1, Otf-1, POU domain class 2 transcription factor 1

ID gène: 5451

NCBI Accession: NP_002688

UniProt: P14859