Butyrylcholinesterase anticorps
Aperçu rapide pour Butyrylcholinesterase anticorps (ABIN568155)
Antigène
Voir toutes Butyrylcholinesterase (BCHE) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- The antibody recognizes Butyrylcholinesterase from Human Serum. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, single Radial Immunodiffusion (Ouchterlony), block titration, ELISA, Immunoblotting and Enzyme Inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.
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Purification
- Solid Phase Affinity Chromatography
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Immunogène
- Butyrylcholinesterase isolated and purified from Human serum. Freund’s complete adjuvant is used in the first step of the immunization procedure.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Restore by adding 0.5 mL of sterile distilled water, Prepare working dilutions by adding sterile phosphate buffered saline (PBS, ph 7.2) and preferably use the same day.
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Concentration
- 2.0 mg/mL
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Buffer
- PBS, pH 7.2 stabilized with Dextran, without preservatives and foreign proteins
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Agent conservateur
- Without preservative
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody lyophilized at 2-8 °C Reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
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- Butyrylcholinesterase (BCHE)
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Autre désignation
- Cholinesterase
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Sujet
- Butyrylcholinesterase is synthetizised in the liver, and is predominantly found in serum, liver and pancreas. This enzyme is a tetrameric glycoprotein (molecular mass of 350 kDa), and consists of four subunits. Defects in Butyrylcholinesterase are the cause of a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics.Synonyms: Acylcholine acylhydrolase, BCHE, Butyrylcholine esterase, CHE1, Choline esterase II, Pseudocholinesterase
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ID gène
- 590
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NCBI Accession
- NP_000046
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UniProt
- P06276
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Pathways
- Peptide Hormone Metabolism
Antigène
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