Glutathione Reductase anticorps (Biotin)

N° du produit ABIN568226

Détail du produit anti-Glutathione Reductase anticorps (Biotin)

Antigène: Glutathione Reductase (GSR)

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutathione Reductase est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Dot Blot (DB), Immunodiffusion (ID), Radioimmunoassay (RIA)

Specificité: The antibody recognizes Glutathione Reductase from Baker's yeast. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, single Radial Immunodiffusion (Ouchterlony), block titration, ELISA, Immunoblotting and Enzyme Inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.

Attributs du produit: Molar Ratio: Biotin/IgG ~6.2

Purification: Ammonium Sulphate Precipitation and Ion Exchange Chromatography

Immunogène: Glutathione Reductase isolated and purified from Baker's Yeast. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore by adding 1.0 mL of sterile distilled water

Concentration: 10.0 mg/mL

Buffer: PBS, pH 7.2 without preservatives and foreign proteins

Agent conservateur: Without preservative

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.

Détails sur Glutathione Reductase

Antigène: Glutathione Reductase (GSR)

Autre désignation: Glutathione Reductase (GSR Produits)

Synonymes: anticorps GR, anticorps ATGR2, anticorps EMB2360, anticorps glutathione reductase, anticorps AI325518, anticorps D8Ertd238e, anticorps Gr-1, anticorps Gr1, anticorps DDBDRAFT_0168952, anticorps DDBDRAFT_0231410, anticorps DDB_0168952, anticorps DDB_0231410, anticorps 2151, anticorps CG2151, anticorps DTR, anticorps Dm-TrxR, anticorps DmTR, anticorps DmTrx, anticorps DmTrxR, anticorps DmTrxR-1, anticorps Dmel\\CG2151, anticorps Gr, anticorps Trx, anticorps TrxR, anticorps TrxR-1, anticorps Trxr1, anticorps anon-WO03040301.185, anticorps anon-WO03040301.187, anticorps dTrxR, anticorps dmtrxr-1, anticorps gr, anticorps l(1)G0154, anticorps l(1)G0379, anticorps l(1)G0477, anticorps l(1)G0481, anticorps trxr-1, anticorps gor1, anticorps glutathione reductase, gro-2, anticorps glutathione reductase, anticorps glutathione-disulfide reductase, anticorps GR; GRase, anticorps mitochondrial glutathione reductase Pgr1, anticorps Glutathione reductase (GR) (GRase), anticorps Thioredoxin reductase-1, anticorps glutathione-disulfide reductase family protein, anticorps glutathione reductase 1, anticorps GR, anticorps gor, anticorps GSR, anticorps GSR1, anticorps Gsr_2, anticorps Gsr, anticorps GSHR1, anticorps gsr, anticorps LbGR, anticorps pgr1, anticorps GSHR2, anticorps GLR2, anticorps Bcen_2392, anticorps RPE_1989, anticorps HCAG_02219, anticorps SJAG_01162, anticorps Trxr-1, anticorps PF14_0192, anticorps POPTR_0001s14480g, anticorps gsr1

Sujet: Glutathione reductase (GR) is a member of pyridine nucleotide-disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione(GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+ ?2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.Synonyms: GLUR, GR, GRD1, GRase, GSR

ID gène: 856014

NCBI Accession: NP_015234

UniProt: P41921

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis