Ancient Ubiquitous Protein 1 anticorps (AA 229-410)

N° du produit ABIN5684097

Cet anticorps Souris Monoclonal détecte spécifiquement Ancient Ubiquitous Protein 1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Ancient Ubiquitous Protein 1 anticorps (AA 229-410) (ABIN5684097)

Antigène: Ancient Ubiquitous Protein 1 (Aup1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ancient Ubiquitous Protein 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1H6A1

Détail du produit anti-Ancient Ubiquitous Protein 1 anticorps

Épitope: AA 229-410

Fonction: AUP1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human AUP1 (AA: 229-410) expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Ancient Ubiquitous Protein 1

Antigène: Ancient Ubiquitous Protein 1 (Aup1)

Autre désignation: AUP1

Sujet: The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.

Poids moléculaire: 53 kDa

UniProt: Q9Y679