LAG3 anticorps (N-Term) (Atto 590)

N° du produit ABIN5688372

Cet anticorps Souris Monoclonal détecte spécifiquement LAG3 dans ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour LAG3 anticorps (N-Term) (Atto 590) (ABIN5688372)

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAG3 est conjugé à/à la Atto 590

Application: Immunocytochemistry (ICC)

Clone: 17B4

Détail du produit anti-LAG3 anticorps (Atto 590)

Épitope: N-Term

Specificité: Recognizes human LAG-3.

Pureté: > 95% (SDS-PAGE)

Immunogène: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

Détails sur LAG3

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Autre désignation: LAG-3

Sujet: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

ID gène: 3902

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints