Retinoic Acid Receptor gamma anticorps (N-Term)

N° du produit ABIN5688663

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoic Acid Receptor gamma dans WB. Il présente une réactivité envers Humain, Souris, Chien et Boeuf (Vache).

Aperçu rapide pour Retinoic Acid Receptor gamma anticorps (N-Term) (ABIN5688663)

Antigène: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Reactivité: Humain, Souris, Chien, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoic Acid Receptor gamma est non-conjugé

Application: Western Blotting (WB)

Clone: 763

Détail du produit anti-Retinoic Acid Receptor gamma anticorps

Épitope: N-Term

Purification: Protein G purified

Immunogène: Peptide corresponding to amino acid residues from the N-terminal region of human retinoic acid receptor, a-isotype.

Isotype: IgG1

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with bovine, canine and mouse tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Retinoic Acid Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur Retinoic Acid Receptor gamma

Antigène: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Autre désignation: Retinoic Acid Receptor

Sujet: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRalpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Poids moléculaire: 48 kDa

ID gène: 5914

UniProt: P10276

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size