Retinoid X Receptor anticorps

N° du produit ABIN5688670

L’anticorps anti-Retinoid X Receptor Monoclonal Souris est utilisé pour la détection de Retinoid X Receptor dans des échantillons de Humain, Souris, Rat et Boeuf (Vache). Il a été validé pour WB.

Aperçu rapide pour Retinoid X Receptor anticorps (ABIN5688670)

Antigène: Retinoid X Receptor

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Application: Western Blotting (WB)

Clone: 1373

Détail du produit

Purification: Protein G purified

Immunogène: Hinge peptide from human retinoid X receptor, y-isotype.

Isotype: IgG1

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with bovine, mouse, non-human primate and rat tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Retinoid X Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détail du antigène

Antigène: Retinoid X Receptor

Sujet: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Poids moléculaire: 48 kDa

ID gène: 6258

UniProt: P48443