SLC6A1 anticorps (C-Term)

N° du produit ABIN5688853

L’anticorps Lapin Polyclonal anti-SLC6A1 a été validé pour WB et IHC. Il convient pour détecter SLC6A1 dans des échantillons de Rat et Souris.

Aperçu rapide pour SLC6A1 anticorps (C-Term) (ABIN5688853)

Antigène: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC6A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SLC6A1 anticorps

Épitope: C-Term

Purification: Affinity Purified

Immunogène: Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will also react with mouse tissue based on the fact that this species has 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: GAT-1 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur SLC6A1

Antigène: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Autre désignation: GAT-1

Sujet: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).

Poids moléculaire: 67 kDa

ID gène: 79212

UniProt: P23978