STXBP1 anticorps (pSer515)

N° du produit ABIN5688903

Cet anticorps Lapin Polyclonal détecte spécifiquement STXBP1 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet et Xenopus laevis.

Aperçu rapide pour STXBP1 anticorps (pSer515) (ABIN5688903)

Antigène: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STXBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-STXBP1 anticorps

Épitope: pSer515

Purification: Affinity Purified

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser515 of Munc-18.

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, chicken, human, mouse, non-human primates and Xenopus based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Munc-18 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur STXBP1

Antigène: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Autre désignation: Munc-18

Sujet: Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein (Sassa et al., 1996).

Poids moléculaire: 65 kDa

ID gène: 81804

UniProt: Q62753

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport