GABBR1 anticorps (pSer923)

N° du produit ABIN5688912

Cet anticorps Lapin Polyclonal détecte spécifiquement GABBR1 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris et Boeuf (Vache).

Aperçu rapide pour GABBR1 anticorps (pSer923) (ABIN5688912)

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABBR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GABBR1 anticorps

Épitope: pSer923

Purification: Affinity Purified

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser923 of GABAB R1.

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, human, mouse and non-human primate tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: GABAB Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur GABBR1

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Autre désignation: GABBR1

Sujet: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.

Poids moléculaire: 102 kDa

ID gène: 81657

UniProt: Q9Z0U4

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process