CCL17 anticorps

N° du produit ABIN5689115

Détail du produit anti-CCL17 anticorps

Antigène: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL17 est non-conjugé

Application: Western Blotting (WB), ELISA, Neutralization (Neut)

Purification: Anti-hTARC specific antibody was purified by affinity chromatography employing immobilized hTARC matrix.

Immunogène: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hTARC (human Thymus and Activation Regulated Chemokine).

Information d'application

Indications d'application: Neutralization:
To yield one-half maximal inhibition [ND50] of the biological activity of hTARC (100.00 ng/mL), a concentration of 20.0 - 30 μ,g/mL of this antibody is required.

ELISA:

To detect hTARC by direct ELISA (using 100 μ,L/well antibody solution) a concentration of at least 0.5 μ,g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hTARC.

Sandwich:

To detect hTARC by sandwich ELISA (using 100 μ,L/well antibody solution) a concentration of 0.5 - 2.0 μ,g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Human TARC (XP-5279Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTARC.

Western Blot:
To detect hTARC by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μ,g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hTARC is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: -20 °C

Stockage commentaire: Tarc antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. Avoid repeated freeze-thaw cycles.

Détails sur CCL17

Antigène: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Autre désignation: Tarc (CCL17 Produits)

Synonymes: anticorps A-152E5.3, anticorps ABCD-2, anticorps SCYA17, anticorps TARC, anticorps CCL17, anticorps Abcd-2, anticorps Scya17, anticorps Scya17l, anticorps Tarc, anticorps abcd2, anticorps C-C motif chemokine ligand 17, anticorps chemokine (C-C motif) ligand 17, anticorps ATP-binding cassette sub-family D member 2, anticorps CCL17, anticorps Ccl17, anticorps LOC100537809

Sujet: Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TARC displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. TARC binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells

ID gène: 6361

UniProt: Q92583