TFE3 anticorps (AA 303-307)

N° du produit ABIN5689356

Cet anticorps Lapin Polyclonal détecte spécifiquement TFE3 dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour TFE3 anticorps (AA 303-307) (ABIN5689356)

Antigène: TFE3 (Transcription Factor E3 (TFE3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFE3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TFE3 anticorps

Épitope: AA 303-307

Specificité: This antibody detects endogenous levels of total TFE3 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: TFE3 antibody was raised against a peptide sequence around aa.303~307 (L-D-V-Y-S) derived from Human TFE3.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur TFE3

Antigène: TFE3 (Transcription Factor E3 (TFE3))

Autre désignation: TFE3

Sujet: Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Poids moléculaire: 70 kDa

ID gène: 7030

NCBI Accession: NP_006512

UniProt: P19532