TWIST2 anticorps (AA 26-30)

N° du produit ABIN5689370

Détail du produit anti-TWIST2 anticorps

Antigène: TWIST2 (Twist Homolog 2 (TWIST2))

Épitope: AA 26-30

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TWIST2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous level of total Twist2 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Twist2 antibody was raised against a peptide sequence around aa.26~30 (P-K-R-F-G) derived from Human Twist2.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur TWIST2

Antigène: TWIST2 (Twist Homolog 2 (TWIST2))

Autre désignation: Twist2 (TWIST2 Produits)

Synonymes: anticorps TWIST2, anticorps DERMO1, anticorps FFDD3, anticorps SETLSS, anticorps bHLHa39, anticorps Dermo1, anticorps CDERMO-1, anticorps twist family bHLH transcription factor 2, anticorps twist basic helix-loop-helix transcription factor 2, anticorps TWIST2, anticorps Twist2

Sujet: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Poids moléculaire: 18 kDa

ID gène: 117581

NCBI Accession: NP_476527

UniProt: Q8WVJ9

Pathways: Chromatin Binding