Caveolin-1 anticorps (AA 1155-1159)

N° du produit ABIN5689526

Cet anticorps anti-Caveolin-1 Polyclonal Lapin (ABIN5689526) détecte spécifiquement Caveolin-1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Caveolin-1 anticorps (AA 1155-1159) (ABIN5689526)

Antigène: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caveolin-1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Caveolin-1 anticorps

Épitope: AA 1155-1159

Specificité: This antibody detects endogenous level of total Caveolin-1 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Caveolin-1 (Ab-14) antibody was raised against a peptide sequence around aa.12~16 (H-L-Y-T-V) derived from Human CAVEOLIN-1.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur Caveolin-1

Antigène: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Autre désignation: Caveolin 1

Sujet: The scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.

Poids moléculaire: 24 kDa

ID gène: 857

NCBI Accession: NP_001166366

UniProt: Q03135

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals