Glutamate Receptor 1 anticorps (pSer836)

N° du produit ABIN5689695

Cet anticorps Lapin Polyclonal détecte spécifiquement Glutamate Receptor 1 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Glutamate Receptor 1 anticorps (pSer836) (ABIN5689695)

Antigène: Glutamate Receptor 1 (GLUR1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutamate Receptor 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Glutamate Receptor 1 anticorps

Épitope: pSer836

Specificité: This antibody detects endogenous level of GluR1 only when phosphorylated at serine 836.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Immunogène: GluR1 (phospho-Ser836) antibody was raised against a peptide sequence around phosphorylation site of serine 836 (S-E-Sp-K-R) derived from Human GluR1.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur Glutamate Receptor 1

Antigène: Glutamate Receptor 1 (GLUR1)

Autre désignation: GluR1

Sujet: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 110 kDa

ID gène: 2890

NCBI Accession: NP_000818

UniProt: P42261

Pathways: Signalisation PI3K-Akt