BimEL anticorps (AA 20-70)

N° du produit ABIN5689905

Cet anticorps Lapin Polyclonal détecte spécifiquement BimEL dans ELISA, WB, ICC et IF. Il présente une réactivité envers Rat, Humain et Souris.

Aperçu rapide pour BimEL anticorps (AA 20-70) (ABIN5689905)

Antigène: BimEL

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BimEL est non-conjugé

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-BimEL anticorps

Épitope: AA 20-70

Specificité: Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist, this antibody only detects the Bim EL isoform.

Purification: Bim EL Antibody is affinity chromatography purified via peptide column.

Immunogène: Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim.

The immunogen is located within amino acids 20 - 70 of Bim EL.

Isotype: IgG

Information d'application

Indications d'application: Bim EL antibody can be used for detection of Bim EL by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Bim EL Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Bim EL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur BimEL

Antigène: BimEL

Autre désignation: Bim EL

Sujet: Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).

Poids moléculaire: Predicted: 22 kDa

Observed: 24 kDa

ID gène: 10018

NCBI Accession: NP_619527

UniProt: O43521