DNAJC13 anticorps (AA 1940-1990)

N° du produit ABIN5689948

L’anticorps anti-DNAJC13 Polyclonal Lapin est utilisé pour la détection de DNAJC13 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour DNAJC13 anticorps (AA 1940-1990) (ABIN5689948)

Antigène: DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJC13 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DNAJC13 anticorps

Épitope: AA 1940-1990

Specificité: DNAJC13 antibody is human and mouse reactive. At least two siforms of DNAJC13 are known to exist, this antibody will detect both isoforms. DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.

Purification: DNAJC13 antibody is affinity chromatography purified via peptide column.

Immunogène: DNAJC13 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DNAJC13.

The immunogen is located within amino acids 1940 - 1990 of DNAJC13.

Isotype: IgG

Information d'application

Indications d'application: DNAJC13 antibody can be used for detection of DNAJC13 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DNAJC13 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: DNAJC13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur DNAJC13

Antigène: DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))

Autre désignation: DNAJC13

Sujet: DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans (1). It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles (2). DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor (3).

Poids moléculaire: Predicted: 249 kDa

Observed: 249 kDa

ID gène: 23317

NCBI Accession: NP_056083

UniProt: O75165